This is the world’s first gene therapy for arthritis and it has been approved in South Korea and US trials are due
AN arthritis treatment which injects genes directly into affected joints could help millions.
The jabs deliver lab-created DNA which creates “treatment genes” within the joint.It has been used for osteoarthritis and rheumatoid arthritis with patients showing a “dramatic clinical improvement”.
The jabs, which can be self-administered, spare the rest of the body from being exposed to drugs.
Professor Terence Flotte,editor in chief of Human Gene Therapy, where the review study is published, said: "Arthritis is the most common disorder that is likely to be treatable with gene therapy within the next several years.
"This latest instalment of our Target Organ series provides a comprehensive review of the optimal platforms for treating these potentially disabling disorders."
The jab injects 'treatment genes' directly to the affected area
Traditional non-surgical treatments for the most common types of arthritis include using painkillers, anti-inflammatory drugs and corticosteroids.
The gene therapy technique was previously challenging because of the speed injected treatments leave the synovial space, which is formed of connective tissue around the joint.
Previous studies have showed a 'dramatic clinical improvement' in 30 to 40 per cent of arthritis patients who used similar treatments, the researchers said.
The study said: "Gene transfer provides a way to overcome the problem of delivering biologics to joints in a focal, local, sustained, and efficient manner.
"This capability offers new ways to address some of the most common, debilitating, and intractable conditions of modern medicine.
"Although gene therapy for arthritis and related conditions has been discussed for more than 25 years, progress toward clinical application has been slow.
"Its approval should stimulate interest in the entire field leading to more rapid development of genetic drugs for conditions that affect joints."
The world’s first gene therapy for arthritis has been approved in Korea and US trials are due.
https://www.thesun.co.uk/news/5411519/new-arthritis-jab-goes-directly-to-affected-area-could-help-millions/
The gene therapy technique was previously challenging because of the speed injected treatments leave the synovial space, which is formed of connective tissue around the joint.
Previous studies have showed a 'dramatic clinical improvement' in 30 to 40 per cent of arthritis patients who used similar treatments, the researchers said.
The study said: "Gene transfer provides a way to overcome the problem of delivering biologics to joints in a focal, local, sustained, and efficient manner.
"This capability offers new ways to address some of the most common, debilitating, and intractable conditions of modern medicine.
"Although gene therapy for arthritis and related conditions has been discussed for more than 25 years, progress toward clinical application has been slow.
"Its approval should stimulate interest in the entire field leading to more rapid development of genetic drugs for conditions that affect joints."
The world’s first gene therapy for arthritis has been approved in Korea and US trials are due.
https://www.thesun.co.uk/news/5411519/new-arthritis-jab-goes-directly-to-affected-area-could-help-millions/
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