Low-Dose Radiation Therapy: A Step Toward Arthritis Relief?

From cityofhope.org

Arizona arthritis rates are higher than those nationally. Find out whether low-dose radiation therapy may help ease osteoarthritis symptoms.

Arthritis is a common condition, affecting more than 60 million people across the United States. In Arizona, the arthritis rates are higher than the national average: Approximately 30% of women and 21% of men have some form of the disease. One possible reason for this is that individuals with arthritis often move to warmer, dryer climates, like Arizona, in search of symptom relief.

Osteoarthritis treatment typically begins with conservative approaches such as physical rehabilitation, weight loss and moderate levels of physical activity. These are frequently followed by the use of nonsteroidal anti-inflammatory drugs (NSAIDs). However, these initial strategies may not provide sufficient symptom relief — or their effectiveness may diminish over time.

One evidence-based treatment option has been shown to reduce pain and improve joint function in people with osteoarthritis: Low-dose radiation therapy (LDRT).

“LDRT works by reducing joint inflammation, resulting in decreased pain, improved mobility and enhanced quality of life,” explains Michael Christensen, M.D., M.B.A., radiation oncologist at City of Hope® Cancer Center Phoenix. “This is especially true in patients who have not responded well to conventional therapies like NSAIDs, physical therapy or weight loss.”

Arthritis is more common in Arizona than in most other states – and it can significantly impact patients’ daily lives.

• More than 23% of Arizonans, or approximately 1.6 million people, have been diagnosed with arthritis
• About 850,000 Arizonans experience daily limitations due to their arthritis
• Approximately 42% of those with arthritis report work-related limitations caused by the condition

What Is Low-Dose Radiation Therapy for Osteoarthritis?

While radiation therapy is commonly associated with cancer treatment, it has been used for decades to treat a wide range of non-cancerous condition as well. As the name suggests, LDRT involves significantly lower doses of radiation than those used in cancer care. When used to treat osteoarthritis, LDRT can target the joints most affected by the disease.

“Low-dose radiation therapy helps relieve pain and inflammation in osteoarthritis by modulating the body’s immune response,” says Dr. Christensen.

LDRT may help relieve arthritis symptoms — such as joint pain and reduced mobility — through several biological mechanisms:

• Reducing the activity of inflammatory cells, including macrophages and neutrophils
• Slowing down the production of pro-inflammatory proteins
• Enhancing the immune system’s ability to control inflammation and preserve healthy joint tissue

Dr. Christensen notes that approximately 70% of patients experience meaningful symptom relief, with the greatest improvement typically occurring between six and 12 weeks after treatment.

How Is LDRT Administered?

LDRT is delivered externally using focused radiation beams. The process is non-invasive and pain free, with each course typically consisting of six sessions over two to three weeks.

“LDRT is an outpatient treatment, where each session lasts just 10 to 15 minutes,” says Dr. Christensen. “Because it’s so well tolerated, most patients can resume normal activities immediately after each treatment.”

If a patient experiences partial relief or symptoms return, a second course of LDRT may be considered eight to 12 weeks after the initial treatment.

Low-Dose Radiation Therapy Side Effects

One of the key benefits of LDRT for osteoarthritis is its low risk of side effects.

“The radiation doses used for LDRT are much lower than the threshold associated with tissue damage or secondary malignancy,” Dr. Christensen explains.

Side effects are rare and generally mild, with the most commonly reported being temporary skin redness or mild fatigue. Importantly, there is no evidence that LDRT increases the risk of cancer in older adults.

https://www.cityofhope.org/locations/phoenix/low-dose-radiation-therapy-for-osteoarthritis 

4 surprising arthritis triggers hiding in toothpaste

From rollingout.com

Common oral care products may trigger inflammatory responses in susceptible individuals 

Photo credit: shutterstock.com/PeopleImages.com - Yuri A

The morning ritual of brushing teeth seems harmless enough, but emerging connections between certain toothpaste ingredients and autoimmune conditions have raised important health questions. While maintaining oral hygiene remains crucial, understanding potential risks helps consumers make informed choices about their dental care products.

The relationship between oral health and systemic inflammation has gained attention as scientists explore how everyday products might influence immune system function. Certain compounds commonly found in toothpaste may contribute to inflammatory responses that could potentially trigger or worsen autoimmune conditions like rheumatoid arthritis in susceptible individuals.

Antimicrobial agents disrupt immune balance

1. Triclosan, a widely used antimicrobial agent, appears in numerous toothpaste formulations designed to combat bacteria and prevent gum disease. While effective at killing harmful microorganisms, this compound may also disrupt the delicate balance of beneficial bacteria in the mouth and throughout the body.

The human microbiome plays a crucial role in immune system regulation. When antimicrobial agents eliminate both harmful and beneficial bacteria indiscriminately, the resulting imbalance can trigger inflammatory responses that may contribute to autoimmune dysfunction.

Triclosan has been detected in blood samples and urine, indicating that it absorbs through oral tissues during routine brushing. This systemic exposure means the compound can potentially influence immune function throughout the body, not just within the mouth.

The chemical structure of triclosan allows it to persist in body tissues, potentially causing cumulative effects over time. Regular exposure through daily toothpaste use may create chronic low-level inflammation that contributes to autoimmune disease development in genetically predisposed individuals.

Fluoride compounds trigger inflammatory pathways

2. Fluoride preparations in toothpaste, while beneficial for preventing tooth decay, may inadvertently stimulate inflammatory responses in some people. Different fluoride compounds used in oral care products can interact with immune system cells in ways that promote inflammation.

Sodium fluoride, the most common form found in toothpaste, can accumulate in joint tissues over time. This buildup may contribute to the inflammatory processes characteristic of rheumatoid arthritis, particularly in individuals with genetic susceptibilities to autoimmune conditions.

The mechanism involves fluoride’s ability to interfere with enzyme systems that regulate inflammatory responses. When these regulatory systems become disrupted, the immune system may begin attacking healthy joint tissues, leading to the chronic inflammation seen in rheumatoid arthritis.

Excessive fluoride exposure has been linked to skeletal fluorosis, a condition that shares some similarities with rheumatoid arthritis symptoms, including joint pain and stiffness. This overlap suggests potential pathways through which fluoride might contribute to autoimmune joint problems.

Surfactants alter immune cell function

3. Sodium lauryl sulfate (SLS), the foaming agent that creates toothpaste’s characteristic lather, may influence immune system behaviour through its interaction with cellular membranes. This detergent-like compound can penetrate oral tissues and potentially reach systemic circulation.

SLS has demonstrated the ability to alter cell membrane permeability, which could affect how immune cells communicate and respond to threats. Disrupted cellular communication may contribute to the immune system confusion that characterizes autoimmune diseases.

The compound’s harsh cleansing action may also damage the protective barriers of oral tissues, creating opportunities for bacteria and other inflammatory triggers to enter the bloodstream. This increased bacterial translocation could stimulate chronic immune responses that contribute to autoimmune disease development.

Regular exposure to SLS through daily brushing may create ongoing irritation and inflammation in oral tissues. This chronic inflammatory state could serve as a persistent trigger for systemic autoimmune responses in susceptible individuals.

Artificial preservatives activate immune responses

4. Chemical preservatives used to extend toothpaste shelf life may inadvertently trigger immune system activation. Compounds like parabens, formaldehyde-releasing agents, and other synthetic preservatives can act as immune system irritants.

These preservatives may function as haptens – small molecules that become antigenic when they bind to proteins in the body. Once this binding occurs, the immune system may begin producing antibodies against the preservative-protein complexes, potentially leading to autoimmune reactions.

The cumulative effect of daily exposure to multiple preservatives through oral care products may overwhelm the body’s natural detoxification systems. This toxic burden could contribute to the chronic inflammation that underlies autoimmune conditions like rheumatoid arthritis.

The oral-systemic connection

The mouth serves as a gateway between the external environment and internal body systems. Ingredients absorbed through oral tissues can quickly enter systemic circulation, influencing immune function throughout the body.

Gum disease and oral inflammation have already been linked to increased rheumatoid arthritis risk, suggesting that the oral environment plays a significant role in autoimmune disease development. Adding potentially inflammatory toothpaste ingredients to an already compromised oral environment may amplify these risks.

Making safer choices for oral care

Natural alternatives to conventional toothpaste formulations may reduce exposure to potentially problematic ingredients. Products free from triclosan, SLS, artificial preservatives, and excess fluoride offer options for those concerned about autoimmune disease risks.

Simple ingredients like baking soda, sea salt, and essential oils can provide effective cleaning action without the inflammatory potential of synthetic compounds. However, consulting with dental professionals ensures that alternative oral care approaches maintain adequate protection against tooth decay and gum disease.

Understanding these connections empowers consumers to make informed decisions about their oral care products while maintaining the dental hygiene necessary for overall health.

https://rollingout.com/2025/07/26/arthritis-triggers-hiding-in-toothpaste/

Is there a cure for rheumatoid arthritis?

From medicalnewstoday.com 

Rheumatoid arthritis (RA) does not have a cure, and is a progressive condition, which means it continually develops over time.

Treatment for RA may help to slow the condition’s progression and aims to prevent irreversible joint damage. People with RA who do not have treatment may experience disability and a less favourable outlook.

Research suggests that around 40% of people with RA have functional disability that affects their daily lives and ability to work within 10 years of a diagnosis.

Seeking early treatment, which means within six months of first experiencing symptoms, can improve a person’s joint functioning and may lead to lower levels of swollen, tender joints. It also decreases the risk of bone erosions.

Early treatment can also increase a person’s chance of remission, a period in which they have no signs or symptoms of the disease. Some people may choose to slowly decrease treatment if they achieve remission.

However, even late treatment can offer benefits and significantly improve a person’s outlook. People with RA tend to have similar mortality rates if they have treatment, whether it is early or later.

Healthcare professionals may recommendTrusted Source a combination of treatments for someone with RA. A person’s treatment plan may change over time as their condition progresses. Treatment goals tend to be:

• pain relief
• lower inflammation and swelling
• improve daily functioning
• slow, stop, or prevent joint damage
• slow, stop, or prevent organ damage, including a decreased risk of heart and vascular diseases

A doctor may recommend the following treatment options:

• physical therapy
• occupational therapy
• medications, such as:
  • anti-inflammatory drugs
  • corticosteroids
  • disease-modifying antirheumatic drugs (DMARDs)
  • biologics
  • Janus kinase (JAK) inhibitors
• joint surgery
• nutrition consult

People with RA also benefit from regular exercise, which may involve creating a tailored exercise plan, stress reduction, and dietary changes.

A person’s healthcare team will continually monitor them and adjust the treatment plan when necessary. It is important for someone with RA to attend regular check-ups, which may involve blood tests, imaging tests, bone health assessments, and more.

People with RA may also develop complications that require treatment and affect a person’s quality of life and outlook. Common complications of RA include the following:

• irreversible joint damage
• risk of cardiovascular disease, which can cause stroke or heart attack
• vasculitis, in which inflammation damages blood vessels
• osteoporosis, which involves weakened bones
• interstitial lung disease, a progressive lung condition
• cancerous tumours
• Sjögren’s disease, an autoimmune disease in which the immune system attacks moisture-producing glands

Anyone who develops symptoms of RA can benefit from speaking with a healthcare professional to create a treatment plan as quickly as possible.

People with RA can also benefit from speaking with their healthcare team if they develop new symptoms or challenges with their daily function. A doctor may suggest making changes to their current treatment plan.

https://www.medicalnewstoday.com/articles/rheumatoid-arthritis-cure?utm_source=ReadNext#1

12 of the best foods for bone health

From restless.co.uk

Maintaining strong bones is important for overall health and mobility, and reducing the risk of conditions like osteoporosis. Alongside exercising regularly and maintaining a healthy weight, diet is key for bone health – and research shows that certain foods may be particularly beneficial.

With this in mind, we’ve partnered with the Royal Osteoporosis Society (ROS) to bring you 12 of the best foods for bone health. The ROS is the UK’s largest national charity dedicated to improving the diagnosis, treatment, and equipping people with the information and support needed to help them look after their bones. 

What nutrients are important for bone health?

Eating a balanced diet is the most important foundation for bone health. However, several nutrients are particularly helpful for building healthy bones. We’ll cover some of these below.

Calcium

Calcium is the most abundant mineral in the body and is essential for general body function – particularly for bone health. Roughly 99% the body’s calcium is found in the bones, making it key for keeping them strong and healthy.

You can read more about the role of calcium in bone health on the ROS website. The ROS also has a useful guide to identifying calcium-rich foods.

Vitamin D

The body relies on vitamin D to absorb and store calcium in skeletal tissue. This means that, without enough vitamin D, we can’t enjoy the full benefits of upping our calcium intake.

You can read more about the role of vitamin D in bone health on the ROS website. They also have a guide to choosing vitamin D-rich foods.

Protein

Multiple studies have linked high-protein diets with bone health benefits for bone health. In particular, with better bone density later in life and a reduced risk of osteoporosis and fractures.

This is mainly because protein is a major part of bone mass and volume. You can read more about the role of protein in bone health on the ROS website.

B vitamins

According to the ROS, B vitamins are important for bone health because, among other things, they help produce bone-building cells, regulate calcium absorption, and control homocysteine levels (a marker of inflammation).

Vitamins C and E

Vitamins C and E are among the most powerful antioxidants, helping to protect body cells (including bone cells) from damage caused by free radicals (unstable molecules). According to the ROS, if left to build up, free radicals can weaken bones.

Vitamin C also helps the body produce bone-forming cells and is involved in collagen production – a type of protein needed for bone formation.

Vitamin K

The ROS lists vitamin K as another nutrient worth prioritising for bone health – largely because it activates a protein called osteocalcin, which helps build and heal bones.

Fatty acids

Fatty acids, such as omega-3 and omega-6, help the body absorb vitamins like D, E, and K and are thought to promote healthy bones.

Potassium

Potassium has been found to promote healthy bones by reducing the amount of calcium lost in urine. Studies have suggested that it can reduce calcium loss in bones.

Manganese and other trace elements

Research has found that people with osteoporosis often have low levels of trace elements such as manganese, zinc, and copper.

Head over to the ROS website to read more about minerals for bone health.

12 of the best foods for bone health

Now we know some of the most important nutrients for bone health, what are some of the best food sources?

Note: This is not an exhaustive list. Check out the ROS’ guide to nutrition for bones to learn more, which also includes information on foods to avoid. Or, check out their collection of bone-healthy recipes.

1. Dried figs

Dried figs are a good source of calcium, potassium, and magnesium – all of which help to build strong, healthy bones. They’re particularly rich in calcium, with some studies showing they contain over three times as much as other fruits. Dried figs are also high in antioxidants, which help prevent cell damage.

Dried figs make a delicious snack alongside cheese and can be incorporated into various recipes, such as granola bars.

2. Fatty fish

Fatty fish, such as salmon, sardines, and mackerel, are beneficial for bone health because they contain calcium and vitamin D, and are rich in omega-3 fatty acids. Take this study, which found fatty fish had protective effects on hip bone mineral density in older adults.

Check out this delicious baked salmon recipe from the ROS, served with roasted peppers and potatoes if you’d like to up your intake.

3. Tofu

Studies suggest that soy-based foods such as tofu may improve bone health, particularly in women. For example, in this study, higher soy intake was linked with better bone mineral density in postmenopausal women.

Soy is a great source of calcium, protein, and polyphenols (powerful antioxidants), which research suggests that it may help prevent bone disease.

Tofu is delicious and versatile; it makes a tasty addition to various recipes, including curries, stir-fries, and wraps. Why not try these curried tofu wraps from the ROS?

4. Chia seeds

Though tiny, chia seeds are packed with several bone-boosting nutrients, including magnesium, phosphorus, calcium, and omega-3.

In this study, rats that ate chia seeds daily for 13 months had significantly higher bone mineral density than a control group. Researchers put these effects largely down to the chia seeds’ omega-3 content.

So why not try adding a sprinkle of chia seeds to your breakfast? Or make an indulgent and healthy chia pudding?

5. Almonds

Almonds are full of several bone-boosting nutrients, including calcium, copper, magnesium, protein, zinc, manganese, and vitamin K. So much so that experts recommend eating almonds to make sure you get enough of these nutrients.

Almonds make a fantastic snack and can also be enjoyed in various recipes, including this tasty prune and almond mixed grain biriyani from the ROS. yohe ROS community

6. White beans

Alongside being a rich source of fibre and protein, white beans (such as cannellini beans) contain a good amount of calcium.

White beans are delicious in soups and curries. Check out our list of hearty bean recipes for inspiration.

7. Dairy products

Dairy products, including milk, cheese, and yoghurt, are some of the best sources of calcium around. Many dairy products are also fortified with vitamin D.

8. Leafy green vegetables

Green leafy vegetables, including broccoli, kale, collards, cabbage, and Swiss chard, are a great source of calcium, as well as several key vitamins and minerals like magnesium and vitamins C and K.

To up your intake, why not add a serving of leafy greens to your dinner? Or blitz them into a pasta sauce if you’d prefer to mask their taste!

9. Bell peppers

According to research, bell peppers may help protect bone and cartilage cells – largely due to their high vitamin C content.

Bell peppers also contain manganese and other trace minerals, which are linked with a lower risk of osteoporosis.

There are plenty of ways to enjoy bell peppers; for example, served with hummus, in a crunchy salad, or as part of a hearty recipe.

10. Prunes

Studies have linked prunes with improved bone health, largely because of their high vitamin K and potassium content, and anti-inflammatory properties. For example, this study found that post-menopausal women who ate five to six prunes daily maintained better bone mineral density in their hips.

Prunes can be enjoyed as a snack on their own or in various baking recipes. Why not try this prune and passionfruit drizzle cake from the ROS?

11. Grapes

Grapes contain several vitamins and minerals that may help prevent osteoporosis, including manganese, potassium, and vitamins B, C, and K.

This study found that animals fed a grape-rich diet had stronger, thicker thighbones and better calcium retention in their bones. Another eight-week study revealed that rats who ate freeze-dried grape powder had improved bone absorption and calcium retention.

Grapes are also a brilliant source of resveratrol, a type of polyphenol believed to improve bone density. In this two-year study of post-menopausal women, taking resveratrol twice a day improved bone mineral density, slowed bone loss, and reduced the risk of major fractures.

12. Blueberries

In this study, blueberries were found to improve bone health and increase bone mineral density in postmenopausal women. These benefits may be linked to blueberries’ polyphenol content, which has been found to help prevent bone loss and increase bone formation.

Blueberries make a delicious snack on their own and can be added to several recipes, too. Enjoy them as a sweet breakfast topper or with a serving of Greek yoghurt and honey.

Final thoughts…

Maintaining strong, healthy bones is important for overall health and quality of life. And luckily, there are many foods to help keep them in top condition.

For more support, you might like to consider becoming a member of the ROS. From just £3 a month, you’ll receive ongoing advice and support from bone health experts, access to a member magazine with the latest information on osteoporosis, and have the opportunity to connect with others through events and volunteer groups.

https://restless.co.uk/health/healthy-body/the-best-foods-for-bone-health/?contact_id=5e74dd65-8bd7-48a2-a626-ded9a62b692b&utm_source=midweek-email&utm_medium=email&utm_campaign=midweek_email_25-07-24_general&utm_content=midweek_email_25-07-24_general