Monday, 28 April 2025

How to look after arthritic knees – without surgery

From telegraph.co.uk

From diet and exercises to supplements and footwear, three experts reveals how to rescue your knees 

When it comes to osteoarthritis (OA), our knees are most vulnerable; the most complex joints in the body, constructed with four bones and an extensive network of ligaments and muscles, carrying our full body weight. An estimated 5.4 million people in the UK are living with knee OA, but we still don’t know the cause. It’s not a simple case of ‘wear and tear’. Genetics play a role, as well as gender – it’s more common and severe in women – and injuries, such as sports injuries earlier in life or hard physical labour.

“At its base level, OA is inflammation of a joint, a cycle of wear and failure of repair,” explains Mr Saket Tibrewal, a consultant trauma and orthopaedic surgeon at the Cromwell Hospital, who specialises in the knee. “Any joint damage causes inflammation, then you get the release of fluid which carries enzymes which damage the cartilage itself.” Cartilage is the smooth, slippery tissue that cushions the end of our bones to allow them to move freely against each other. The more damaged it becomes, the greater the reaction to further damage – the more fluid, the more enzymes. “Over time, these cycles get progressively worse.”

How can we halt it? Anyone concerned by OA knee pain should first get a diagnosis to establish the state of the joint and, if it is OA, how much cartilage is left. When it comes to self-management, it won’t be possible to reverse, but there are steps that might prevent further deterioration and certainly control symptoms. “If you get it right, you might be able to get through all your active life with a little bit of pain but avoiding surgery,” says David Vaux, the head of therapies and exercise at Arthritis Action and author of Stronger. “If you get it wrong, and especially if you do too much, you potentially accelerate your journey towards a knee replacement.” So what might help?

The best supplements for knee pain

Turmeric

Turmeric is a natural anti-inflammatory,” says Tibrewal. “I tell my patients to take it and for some, it really works.” Curcumin, one of its active components, has anti-inflammatory properties similar to that of non-steroidal anti-inflammatories and a BMJ review of studies of turmeric or curcumin on knee OA found that all recorded improvements in pain and function.

Glucosamine

“This plays a role in building cartilage and might delay it’s breakdown,” says Tibrewal. “Again, not everybody is going to feel a benefit, but some do.” While some research has found that glucosamine reduces OA knee pain, other studies showed little improvement.

Chondroitin

“This can nourish the joint and improve cartilage health,” Tibrewal explains. According to the charity Versus Arthritis, chondroitin has been tested in more than 20 randomised controlled trials and many have shown significant clinical benefits in pain reduction. Although, again, evidence is mixed.

Vitamin D

Vitamin D supplements are important for general bone health,” notes Tibrewal. It may also have anti-inflammatory effects and help maintain the immune system.

Get the right footwear

“Your knee is affected by everything around it,” says Tibrewal. “The ankles, hips, back and spine all feed into it. It’s one whole chain and little imbalances anywhere can affect the knee. People who are flat-footed, or have an incorrect gait, for example will get good symptom relief by addressing that.”

A doctor, occupational therapist, physiotherapist or podiatrist can all give advice here. For those with advanced knee arthritis, Nice guidelines recommend Apos, a foot worn device which looks like a trainer and redistributes pressure in order to reduce pain. (It’s also available privately, often covered by medical insurance.) “Insoles can make a big difference,” says Tibrewal. “I also use a lot of knee bracing. For people who have a lot of wear in one part of the knee, special braces can push the leg straight and take away the pressure.”

Finding the correct footwear is essential. Shoes should have thick soles, enough toe room, and good arch support. “There should be enough cushioning to reduce the impact when you walk,” says Vaux.

Listen to your knees

“Exercise is so important to strengthen the joint but if you feel pain doing something, it’s a request for change,” says Vaux. “Either you did it for too long or it’s the wrong exercise for you. Anyone with OA needs to listen to their body and pace themselves far more than the person on the next treadmill or climbing the escalator in front of you who doesn’t have OA. It’s not fair but it’s important to understand that. Exercise, like medicine, requires the correct dose and for that, you need a diagnosis first, and then a schedule where you ‘train clever’, not hard, doing less exercises but precise ones. We need a little bit of impact for strong bodies, but prolonged impact is detrimental.”

How do you know if pain is ‘healthy’ post-exercise ache or a sign of damage? “It’s normal to have aches after training, but if the knee swells, if you’re losing mobility, if it’s pain that persists, you need to rest the knee,” Vaux continues. When it comes to training muscles around the knee, Vaux suggests twice a week is enough. “But that’s not a golden rule,” he adds. “If you train on Monday and by Thursday, your knee is not feeling great, opt for something non-weight bearing, like cycling, or work on your core and upper body.”

Lose weight

“Offloading the knee through weight reduction is first and foremost the most effective way to alleviate symptoms,” says Mr Rej Bhumbra, a consultant orthopaedic surgeon on the Knee Team at The London Orthopaedic Clinic. “Four times our body weight goes through the knee joint, so even if a patient can lose 5kg, that means 20kg less on the knees. That slight change in weight makes a huge difference.”

However, it isn’t just about weight. “It’s the type of weight you have,” says Bhumbra. “Is your body distribution more fat-based or muscle-based? Muscle bulk around the knee – good quads and hamstrings – offloads the knee.” Research by the Radiological Society of North America (RSNA) has shown that people with strong quads are less likely to need knee replacements.

Sleep well and manage stress

“Sleep is when your body makes its repairs, so prioritise sleep and find ways to manage stress, whether it’s breathing protocols or talking therapies or anything else,” says Vaux. Chronic stress and lack of sleep triggers inflammation and potentially exacerbates pain and the cycle of joint damage. “If you’re always in a state of arousal, our sympathetic nervous system keeps us on alert and the counterbalance, our parasympathetic nervous system, doesn’t have a chance to help our body relax, recover and repair.” A review of 54 studies on the impact of chronic stress on arthritis, found that 41 showed it to be a risk factor for worsening pain and disease progression.

Tailor your diet

“Eat your anti-inflammatories,” says Tibrewal. “Get your omega-3 from oily fish.” The Mediterranean diet is anti-inflammatory while processed meats, sweets and sugary drinks are linked to higher inflammation. Protein is also important. “As we age, our ability to absorb protein is reduced so we should be eating a little bit of protein with every meal,” says Vaux. “The amino acids stored in our skeletal muscular tissue are the repository on which the body draws when recovering from injury and repairing.

Stay flexible

Synovial fluid, also known as joint fluid, is a thick, lubricating liquid found within the knee joint that reduces friction during movement and nourishes the cartilage and surrounding tissue. “Joint health depends on a full range of motion in order to get synovial fluid feeding the surface of our articular cartilage,” says Vaux. “If you lose 10 or 20 per cent of movement, you’ve lost 10 or 20 per cent of that nourishing fluid getting to those areas and that will accelerate wear and tear. Build in a simple night-time and morning stretch routine – you can do them when you’re lying in bed.”

These include:

Knee rotations

Lying on your back with your legs together and knees bent, slowly lower your knees to one side, staying within a comfortable range and not allowing your back to raise up. Bring your knees back to the middle, repeat to the opposite side. Doing so for 2 minutes, this should be slow and rhythmic.

Crossover knee push

Then cross your right ankle over your left knee. Using your right hand to gently press on your right knee, push your knee away from your body until you feel a slight stretch in your right hip and lower back. Then, gently pull your knee toward your belly button before pushing it away again. Continue this movement for one minute before swapping to the left side and repeat the movement.

The best exercises for arthritic knees

When it comes to exercise, low impact is important, such as swimming, cycling, cross-training, and rowing machines. “If you really want to run, if you love to run, I’d recommend grass, not tarmac or treadmill and to limit it, mixing it up with other non-weight bearing cardio,” says Vaux. “Brisk walking is excellent.”

“For strength training, you want to build all the muscles around your knees as a natural brace for that corseting effect, but you also want to strengthen the connective tissue, your ligaments, and tendons that stabilise the knee joint. Isometric exercises – which involve contracting muscles without moving the joint – are ideal for people with knee OA. They give you a really nice contraction without the impact that we want to avoid.”

Static wall sit

“These are great for stabilising our knee joints,” says Vaux. “Depending on your level, start with a slight bend in the knee leaning against the wall, then hold for 30 seconds. Over time, build up to a minute. When that becomes easier, bend your knees a further five degrees and so on. Build this habit into the dead times of your day, like waiting for the kettle or when you’re on hold on your phone. Remember, if it hurts, go higher, or try another exercise.”

Static hip bridge

“This is another great isometric exercise that builds tolerance in the muscle and ligaments of the knee,” says Vaux. “It is also a good alternative if wall-sits make your knees sore.” Lie flat on the floor with your legs bent. Drive through your heels to push your hips upwards as far as you can go.

Slow motion sit down

“When you have got to sit down during the day, do it in slow motion every time to the count of 5 or 6,” says Vaux. “This is an eccentric contraction and it’s gold dust for building stability and preventing knee injuries and the kind of knee pain you experience when walking downstairs.”

Alternate single leg box step-ups

“Build up to four sets of 10 on each leg and when that feels easy, put some bottled water into a pack on your back and build up to four sets of 10 again,” says Vaux. Using the staircase is also fine.

Walking lunge

“Start with own body weight, building up to four lots of 10 lunges for each leg and when this is too easy, add some water bottles to your backpack and start again,” says Vaux.

Single leg balance

“Balancing on one leg can be done anywhere, including waiting for a train or queuing at a check out,” says Vaux. “Use a sink or table if you need a little more support.”

Bouncing

“These are great for balance, muscle and bone health and without the knee impact of jumping,” says Vaux. Facing a desk, a table, kitchen top or sink, hold the surface in front of you with your hands shoulder width apart, bend your knees slightly, with feet shoulder width apart and gently bounce. Keep your back straight and looking up, letting your heels raise up but not letting your toes leave the floor. Start out with 20 bounces and build up to 50 bounces 3-4 times a week.

Stronger:10 exercises for a longer healthier life by David Vaux is available now

https://www.telegraph.co.uk/health-fitness/conditions/bones-joints/how-to-look-after-knees-arthritis/

Sunday, 27 April 2025

Myths and Facts About Rheumatoid Arthritis Treatment

From healthcentral.com

You can’t believe everything you hear about therapies for this autoimmune condition. We asked experts to spell it out 

When rheumatoid arthritis (RA) isn’t well-managed, it can cause painful joint swelling and stiffness, fatigue, and other health issues. Fortunately, there’s a wide variety of excellent treatment options for the autoimmune condition that can help curb inflammation and keep your symptoms at bay. In fact, the RA treatment landscape is so vast (and quickly changing) that it can sometimes feel like a lot to navigate. Especially given all the myths and misinformation floating around out there.

The misconceptions you hear about RA treatment can be confusing half-truths at best—and downright scary falsehoods at worst. And when you’re trying to approach living with RA from the most-informed, empowered place possible? Bad information about treatment is the last thing you need. So we asked rheumatologists to help us separate fact from fiction and debunk some of the most common RA treatment myths.

Myth #1: You Don’t Need Treatment Until Your Symptoms Get Bad

Some people think they only really need to start RA treatment when the pain becomes unmanageable and try to get by on over-the-counter painkillers in the meantime. But delaying treatment isn’t only painful; it can result in permanent damage to your body. “The sooner you start therapy, the more potential you have to prevent joint damage,” says Lesley Davila, M.D., an associate professor of internal medicine in the division of rheumatic diseases at UT Southwestern Medical Centre in Dallas, TX. Putting off treatment also increases the risk of complications. For example, uncontrolled chronic inflammation from RA can raise your risk of heart disease, says Gina Ferrero, M.D., an assistant professor of medicine in the division of arthritis and rheumatic diseases at the Oregon Health & Science University School of Medicine in Portland, OR. But research shows that biologics, for example, decrease the risk of cardiovascular events in people with RA.

So treating RA early and aggressively means symptom relief in the short term, and a healthier body in the long term.


Myth #2: Methotrexate Is the Same as Chemotherapy for Cancer

It’s true that methotrexate, a disease modifying antirheumatic drug (DMARD) that tamps down inflammation, is used as a chemotherapy agent in some kinds of cancer. But that’s hardly the full picture. Methotrexate as a cancer drug is used in much higher doses, Dr. Davila explains. Meanwhile, in smaller doses, it works by reducing symptoms and delaying the progression of RA.

In RA, the typical dose ranges from 10 mg to 25 mg per week, while the doses used for chemotherapy can be up to hundreds of times larger, according to the Arthritis Foundation. So the immune system suppression and side effects are extremely mild by comparison. “We have huge [amounts] of data that, as long as it’s monitored correctly, it’s very safe over long periods of time in rheumatoid arthritis,” Dr. Davila says.

The drug starts working pretty quickly (within six to eight weeks) to ease RA symptoms, it’s easy to take (with a weekly pill or injection), it’s safe and well-tolerated by most people, and it’s relatively inexpensive, according to the Johns Hopkins Arthritis Center.

But there’s a persistent myth that methotrexate is chemotherapy, which scares people away because of the side effects people on chemo tend to have during cancer treatment. “I have people that are very reluctant to consider methotrexate, even though it’s kind of our gold standard and has been around for a very long time,” says Dr. Davila.

Myth #3: Supplements Are Effective Replacements for Prescription Drugs

Dr. Davila gets a lot of questions about natural remedies for RA. Amid the sea of false claims, there is some decent data suggesting certain supplements may provide a modest benefit for some—but they are not a replacement for drug therapies in most cases. “One that we have a little bit of data on is curcumin/turmeric,” Dr. Davila says. Studies show that curcumin, an anti-inflammatory compound found in turmeric, can help reduce symptoms like joint pain and swelling in people with RA. Some research also suggests that omega-3 fatty acids could provide a modest benefit.

But there’s no evidence that supplements can do the job of prescription drugs. “These medications are essential for controlling RA,” says Dr. Ferrero. And if you have more aggressive RA, relying on supplements alone puts you at risk for more joint damage in the long term, Dr. Davila explains. If you’re wondering whether a certain supplement could benefit you, talk to your doctor. And think of it as a potential add-on, not a treatment in itself.

                                                                                     GettyImages/Grace Cary

Myth #4: RA Drug Side Effects Will Ruin Your Life

“All medications can have side effects,” Dr. Ferrero says. “But most patients tolerate RA medications well.” Side effects are often mild. They can go away on their own or often be solved with an adjustment to your dosage or how you take the medication, Dr. Davila says. For instance, some people experience nausea when they start on oral methotrexate. Switching from pills to injections can lessen the effect, Dr. Davila says. So can moving from a morning to evening dose, so that you can sleep through the nausea. Starting at a very low dosage and ramping it up slowly might prevent that issue altogether.

If your side effects are more severe or persistent, your doctor can try you on something else your body agrees with better, Dr. Davila says. So be honest with them about what you’re experiencing.

Myth #5: A Special Diet Can Cure RA

“Anything you do in terms of living your best lifestyle can be helpful,” Dr. Davila says. But again, there’s no replacement for powerful RA meds in preventing disease progression. And while the American College of Rheumatology (ACR) recommends that people with RA eat a Mediterranean-style diet, it’s not the specific diet itself, but the anti-inflammatory foods (like fruits and vegetables) that are included in it that present the greatest health benefits since anything that helps lower the baseline level of inflammation in your body is a bonus with RA. The ACR also recommends minimizing inflammatory foods (like refined carbs and saturated fats) and advises steering clear of other diets, like a vegan or keto diet.

That said, even the most nutritious diet isn’t a substitute for medication. “While a healthy diet and lifestyle are important for managing RA, they are not a cure,” Dr. Ferrero says. “Medications remain essential for effectively controlling RA.” We may learn more about the role of diet as research on the connection between your gut and your immune system grows, Dr. Ferrero adds. But for now, an approach that combines medication and healthy living is best.

Myth #6: RA Medications Cause Cancer

Research does show that some RA drugs may increase the risk of cancer, Dr. Davila says. In one review of 22 studies published in Frontiers in Immunology (pooling data on 371,311 people with RA taking DMARDs), researchers found that people taking conventional synthetic DMARDs had a 15% higher risk of cancer overall. But you have to weigh a slightly increased risk of cancer against the considerable risks of not taking medication, Dr. Davila points out (like joint damage or heart problems from untreated RA).

If you’re at higher risk for cancer (due to family history, for instance), your doctor will factor that into which treatment options they recommend. (The Frontiers in Immunology study found that biologics, for example, did not cause an increased risk of cancer.)

Myth #7: When You Feel Better, You Can Stop Treatment

Once you’re feeling good again, it can be tempting to think you might not need your medication anymore. “I see that a lot,” Dr. Davila says. Studies on people in remission from RA have found that within one year of stopping their treatment, at least 50% will relapse. So some people can stay in remission without drugs for at least a year, Dr. Davila says. “But there are definitely people who feel it immediately.”

If you do experience a flare after going off your treatment, there’s a chance that your medication won’t work as well when you get back on—running the risk of joint damage while you and your doctor work to get you into remission again. So while it’s reasonable to consider stopping medication in some cases, “for the vast majority of people, they probably should be on at least some degree of therapy,” Dr. Davila says.

Myth #8: If Your First Treatment Doesn’t Work, Nothing Will

If your current treatment isn’t working very well, there’s a good chance another one works better for you. “We have just a ton of options right now, which is fabulous,” Dr. Davila says. (Plus, more are in development.)

But finding the best medication for you can involve some trial and error. “At this moment, we really can’t predict what your right drug is going to be,” Dr. Davila says. It’s very individual—so a drug that doesn’t do much for one person can be a fantastic match for another, Dr. Davila says. And some people do best with a multi-pronged approach, she adds—like using more than one drug or adding on physical therapy.

So if you’re unhappy with your current treatment, be open with your doctor. And if you’ve heard anything about RA treatment that concerns you—or that you’re not sure is true—always bring your concerns to your provider. “The underlying message is, have a good relationship with your rheumatologist and have a conversation back and forth,” Dr. Davila says. You’ll navigate your RA treatment choices together to find what works best for you.

https://www.healthcentral.com/condition/rheumatoid-arthritis/myths-and-facts-about-ra-treatment

Saturday, 26 April 2025

Are Topical Anti-Inflammatory Creams Worth the Rub?

From health.clevelandclinic.org

These creams that you apply to your skin can actually help reduce localized pain, swelling and inflammation 

Chronic pain and inflammation can really take a toll on your physical and mental health. Oral nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Motrin®, Advil®) can help reduce pain and inflammation. But they also carry certain risks for cardiovascular and kidney issues, stroke, bleeding and ulcers when you take them for extended periods of time.

“Your risk increases the longer you take NSAIDs as a treatment,” says physiatrist Meredith Konya, MD.

Fortunately, there are topical anti-inflammatory creams that offer the same amount of relief with significantly reduced risks. Dr. Konya explains how topical anti-inflammatory creams should be used and how they work.

What are anti-inflammatory creams?


When you apply topical anti-inflammatory creams directly to the area of your skin that’s causing you pain, they get absorbed by your tissues and joints and disrupt the feeling of pain and inflammation. Every topical anti-inflammatory works differently depending on their active ingredients.

Some of the most common active ingredients include:

  • Diclofenac works as a COX-2 inhibitor by blocking a specific enzyme that causes pain and inflammation. It comes in an over-the-counter gel (Voltaren®), liquid (Pennsaid®) or patch (Flector®). Higher strength versions can be prescribed.
  • Capsaicin is a natural compound that gives chili peppers their heat. It’s used in over-the-counter topical anti-inflammatory creams, lotions, serums and patches. It activates heat sensations in your skin and desensitizes nerve pain over time.
  • Menthol is another common ingredient with anti-inflammatory properties. It’s often used in combination with other active ingredients like methyl salicylate (BenGay®, Icy Hot®) or camphor (Sarna®) to reduce inflammation and swelling.

review of several clinical studies found that Voltaren gel is particularly effective. “In this review, 60% of patients got 50% relief with topical NSAIDs,” reports Dr. Konya. This was similar to the pain relief from oral NSAIDs and better than the placebo.

Do topical anti-inflammatory creams work?

Unlike oral NSAIDs, which reduce inflammation throughout your entire body, topical NSAIDs work to relieve pinpoint, localized pain and swelling in your joints, muscles and tissues.

Although the amount of medication that enters your bloodstream is much lower than if you were to take an oral NSAID, you don’t need a lot of anti-inflammatory cream to experience relief. Topical anti-inflammatories reduce your body’s exposure by almost 90%. This minimizes your risk of experiencing harmful side effects.

What are anti-inflammatory creams used for?

Topical anti-inflammatories come in creams, gels and patches. They’re used to treat pain, stiffness and inflammation associated with a variety of conditions like:

Topical anti-inflammatories come in different strengths and doses, too. Make sure you read their instructions carefully and ask a healthcare provider if you have any questions about how to use them safely.

How long does it take for anti-inflammatory creams to work?

When used as needed or in the short term, these creams can provide immediate pain relief to the affected tissue or joint and the surrounding areas. Unless otherwise recommended by your healthcare provider, you shouldn’t use topical anti-inflammatory creams longer than a week or two. If your pain gets worse or persists beyond that timeframe, make an appointment with your healthcare provider.

Who shouldn’t use anti-inflammatory creams?

Topical anti-inflammatory creams are usually very well-tolerated. If you have difficulty swallowing oral NSAIDs, topical NSAIDs are usually a safe alternative. But approximately 1 in 20 people experience a mild, temporary skin reaction in the form of a rash, redness, dryness or itchiness.

Topical anti-inflammatories shouldn’t be used after open heart surgery either. If you have known cardiovascular disease or kidney disease, talk to your healthcare provider before using these. You also shouldn’t use topical NSAIDs if you’ve taken them in the past and experienced allergic reactions, like:

“Topical NSAIDs are best for people with only a few painful joints,” clarifies Dr. Konya. If you apply the topical anti-inflammatory to several joints, you may exceed the recommended dosage and increase the risk of side effects. “People with arthritis in multiple joints are better off treated with an oral NSAID or acetaminophen (Tylenol®) unless there’s a medical reason they shouldn’t take them.”

https://health.clevelandclinic.org/anti-inflammatory-cream